Medical Devices
Medtronic (NYSE: MDT) announced that results of a study published in the February issue of the Laryngoscope were favorable toward the use of Medtronic"s Straightshot® M4 Microdebrider for powered inferior turbinoplasty. Written by Liu et al from Taipei Medical University, "Microdebrider-Assisted Versus Radiofrequency-Assisted Turbinoplasty," states that patients treated with Medtronic"s microdebrider experienced significantly better long-term outcomes than those who received treatment with a Coblation® radiofrequency device in what is the first three-year study directly comparing long-term efficacy of the two techniques.1
Vetericyn Inc., a California-based animal healthcare company, has announced the launch of its new Vetericyn™ equine product, available in a 16-ounce trigger spray for horses. Vetericyn™ utilizes an FDA-cleared technology that has been used to successfully treat over one million human patients without a single serious adverse effect. Now, the innovative topical wound-care product is available to the animal healthcare market.
The overwhelming majority of all junior doctor rotas will be compliant with the requirements of the European Working Time Directive (EWTD) by 1st August 2009, Health Secretary Andy Burnham announced today.
Thousands of people in England are unaware that they are at risk of developing heart disease due to an undiagnosed genetic condition, says the Royal College of Physicians. Familial hypercholesterolaemia (FH) is an inherited condition causing high levels of LDL cholesterol, and increased risk of coronary heart disease in men in their 50s and women in their 60s. Early treatment with statins has been shown to reduce risk and improve life expectancy to normal.
U.S. Marshals, at the request of the Food and Drug Administration, today seized drug products manufactured by Caraco Pharmaceutical Laboratories Ltd. (Caraco), at the company"s Michigan facilities in Detroit, Farmington Hills, and Wixom. The seizure also includes ingredients held at these same facilities. "The FDA is committed to taking enforcement action against firms that do not manufacture drugs in accordance with our good manufacturing practice requirements," said Janet Woodcock, M.D., director of the FDA"s Center for Drug Evaluation and Research. "Compliance with these standards prevents harm to the public."
"In a new report released yesterday, the government watchdog group Common Cause found that major health care interests have spent upwards of $1.4 million a day to lobby Capitol Hill so far this year," the National Journal reports. This political spending amount represents a 73 percent increase since 2000. In addition, the report finds that campaign contributions to members of Congress jumped $40 million since 2000, to $94 million in the 2008 election cycle (Krigman, 6/24).
The Senate Commerce Committee has found that a flawed payment database produced by a UnitedHealth subsidiary and distributed to other major insurance companies has led insurers to underpay millions of out-of-network claims, forcing patients to make up the difference of health care providers" fees, the Wall Street Journal reports. Aetna, Cigna, WellPoint, and other large insurers used the data to calculate their "reasonable and customary" charges. They also provided UnitedHealth"s subsidiary, Ingenix, with historic data about their payments, which became the foundation of ongoing versions of the flawed payment models.
The New York Times examines a program being offered at an orphanage in Tanzania that provides emotional and physical support for newborns and young children who are at a high risk of death after losing their mothers in infancy. "Africa is full of at least 50 million orphans, the legacy of AIDS and other diseases, war and high rates of death in pregnancy and childbirth," the newspaper writes. "With the numbers increasing every day, Africans are struggling to care for them, often in ways that differ strikingly from the traditional concept of an orphanage in the developed world."
Britain"s workplace safety regulator today warned businesses in the North East of the continued need to put safety first as new figures reveal the number of employees killed at work.
Cirrhosis is a world wide, bad prognosis liver disease and characterized by excessive collagen deposition and liver function damage. In our previous work, p90RSK is observed significantly up-regulated in association with elevated collagen type I levels in rat liver fibrosis. But detail mechanism of this phenomenon is still unknown.
The Denver Post on Friday examined efforts to establish needle-exchange programs in Colorado to reduce the risk of HIV and hepatitis C among injection drug users. According to the Post, 185 cities in Colorado have needle-exchange programs, but legislation that would have legalized needle exchanges statewide did not advance in the Legislature this year. "The issue is more complex than it perhaps first appears," Evan Dreyer, a spokesperson for Gov. Bill Ritter (D), said, adding that "law enforcement and the Colorado Department of Public Health and Environment both expressed serious reservations" about a proposal that would have legalized needle-exchanges statewide. A coalition of public health officials, treatment providers and advocates are increasing efforts to establish a needle-exchange program in Denver, the Post reports. The Denver Drug Strategy Commission in February recommended that Mayor John Hickenlooper consider a pilot needle-exchange program, DDSC Director Karla Maraccini said. The commission is looking at different programs to develop a model following Hickenlooper"s request for additional research. However, Denver District Attorney Mitch Morrissey has concerns that a local needle-exchange program would violate state law, according to Morrissey"s spokesperson Lynn Kimbrough. Eric Brown, a spokesperson for Hickenlooper, added, "Anything in contradiction to city or state law would have to be carefully considered." Proponents of needle-exchange programs say they prevent HIV and hepatitis C, but opponents say they condone injection drug use. Mark Thrun, director of HIV prevention for Denver Public Health, said, adding that needle-exchange programs prevent IDUs from "getting these chronic, potentially fatal diseases" and give public health workers "an opportunity to link them into treatment; and it lessens the economic burden on the already overburdened health care system." Thrun noted that several studies have found that needle-exchange programs do not encourage or prolong injection drug use and make IDUs more likely to seek treatment. In addition, a 2005 CDC study found that 86% of exchange programs make treatment referrals and that more than 80% offer counseling and testing for HIV/AIDS and hepatitis C.Nancy Steinfurth, executive director of the Hep C Connection, noted that an estimated 10% of HIV cases and 70% of hepatitis C cases are transmitted through needles (Auge, Denver Post, 5/15).
As a woman gets older, physical problems are less likely to influence whether she is sexually active than her partner"s health or interest in sex, according to a new study by researchers at the University of California, San Francisco and Kaiser Permanente.
The drug, called olaparib, specifically targets hereditary cancer caused by faulty BRCA1 and BRCA2 genes. The small scale patient trial has shown remarkable benefit for patients with breast, ovarian and prostate cancer.
The American Diabetes Association, the nation"s leading health organization in the fight to stop diabetes, is pleased to announce that the National Employment Lawyers Association has honored Gary Branham, who successfully fought discrimination based on diabetes, as one of three "Workplace Heroes & Heroines." The award honors those who have made a difference in the evolution of employee rights, and advancing equality and justice in the American workplace during the past twenty years. (For more information on this award, see http://www.nela.org.)
Providing reliable evidence of viruses in human blood presently requires time- and labor-intensive molecular-biological procedures. Established methods are particularly hard pushed to produce evidence when the viral burden is very low, for example during a phase of therapy. This could soon change. While developing new types of micro-pumps without movable parts, scientists from the Fraunhofer Institute for Biomedical Engineering IBMT came across an unexpected phenomenon: stable turbulence structures formed in the microscale pump channels. The nano- and microparticles actually intended to verify the pump effect accumulated in large quantities in the channels. The vortex patterns completely filled the whole microchannel, creating a virtually 100% trap for the particles that followed the generated flow profile, although there is a very large cross-section to flow through. "The development of flow vortices is nothing unusual on the macroscopic scale. However, in microchannels the flow lines almost run in parallel," explains Richard Stein from the IBMT. "The question, therefore, was, how is it possible for vortices to be formed from this which were sufficiently stable and effective for the concentration of nanoparticles?"
Veritide Ltd., a developer of innovative biological identification and detection solutions, today reported that new independent data to be presented at the Biodetection Technologies 2009 conference confirm the exceptional accuracy of its Ceeker™ (pronounced "seeker") portable bacterial detection device in discriminating between anthrax spores and similar-looking hoax substances. The data show that in over two weeks of testing at the Midwest Research Institute in Florida, the company"s Ceeker scanner accurately identified 100% of the anthrax samples used and was correct in 95% of tests involving hoax substances. These test results are consistent with similar results produced last year by a New Zealand forensic testing agency, Environmental Science and Research (ESR).
Contrary to predictions, males of high genetic quality are not very successful when it comes to fertilizing eggs. A new study on seed beetles by Swedish and Danish scientists Goran Arnqvist and Trine Bilde shows that when a female mates with several males, the males of low genetic quality are the most successful in fertilizing eggs. The study is published in this week"s issue of Science.
In a review in Science, a University of Rochester Medical Center researcher sorts out the controversy and promise around a dangerous subtype of cancer cells, known as cancer stem cells, which seem capable of resisting many modern treatments.
Although the recorded HIV prevalence in Pakistan is relatively low, health officials are concerned that a concentrated epidemic of the virus among injection drug users could carry over to commercial sex workers and other high risk groups in the country, IRIN/PlusNews reports. To address the issue, the National AIDS Control Program and the United Nations Population Fund recently held a meeting, called the National Consultation on HIV and Sex Work, in an effort to improve HIV prevention efforts targeted at sex workers by consulting with workers in the field.Sex workers at the meeting made various recommendations, including HIV testing, referrals and increased efforts to decrease stigma. The Ministry of Health reports that from 2006 to 2007, female sex workers were at a high risk of HIV in 12 cities across Pakistan. A survey of 4,639 female sex workers found that less than 25% reported condom use; 10% had a partner that had used injection drugs during the past six months; and that illiterate sex workers were less likely to use condoms than those with a higher level of education. A female sex worker at the meeting said, "It is very hard for us to convince [partners] to put on a condom, but I feel that a female condom would put us in a position where we can protect ourselves against HIV and sexually transmitted infections." She added that female condoms are not widely available. Legalizing sex work would make it easier for sex workers to protect their rights, another female sex worker at the conference said. She added that often, outreach workers face barriers from police forces. Daniel Baker, UNFPA"s country representative for Pakistan, said that sex workers should have greater involvement in creating and implementing HIV programs. He added, "The female sex workers have to be in there as managers, workers and leaders to benefit in the long run." Safdar Kamal Pasha with UNFPA agreed that the recommendations from sex workers are critical points to address in future programming. "The female sex workers agreed that there should be vocational training and the means for alternative work opportunities for those who want to move out of sex work, as well as those who are past their prime and do not find sustainability in sex work," Pasha said (IRIN/PlusNews, 5/14).
Researchers at the Yerkes National Primate Research Center, Emory University, have demonstrated for the first time rhesus monkeys and humans share a specific perceptual mechanism, configural perception, for discriminating among the numerous faces they encounter daily. The study, reported in the June 25 online issue of Current Biology, provides insight into the evolution of the critical human social skill of facial recognition, which enables us to form relationships and interact appropriately with others.
In primates including ourselves, the ability to register where others are looking is key in social circles. And, according to a new report published online on June 25th in Current Biology, a Cell Press publication, the way our brains process gaze-direction is much more sophisticated than a simple eyes-right versus eyes-left.
AcademyHealth and the Robert Wood Johnson Foundation have awarded ten scholarships to graduate students who demonstrate outstanding potential to contribute to the field of public health systems research (PHSR).
Pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from the University of
Boehringer Ingelheim announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has issued a positive opinion recommending the approval of a once daily formulation for Mirapexin®/ Sifrol® (pramipexole), in all countries of the European Union, Norway, Iceland and Liechtenstein. The CHMP recommendation states that the new prolonged-release formulation is indicated for treatment of the signs and symptoms of idiopathic Parkinson"s disease, alone (without levodopa) or in combination with levodopa, i.e. over the course of the disease, through to late stages when the effect of levodopa wears off or becomes inconsistent and fluctuations of the therapeutic effect occur (end of dose or "on off" fluctuations).
"Eradicating global poverty starts with the health of the world"s poor," Bill Frist, former U.S. Senate Majority leader and currently a member of the Millennium Challenge Corporation"s (MCC) Board of Directors, writes in a Charlotte Observer opinion piece. "It starts with empowering them physically to contribute to the vitality of their countries," Frist says, which "makes as much good sense for the world"s poor as for our collective international economic growth."Frist says that Obama"s recent proposal of a six-year $63 billion global health initiative is "bold," and the "smart use of res improves the health of the world"s poorest and strengthens the global economic climate for us all." He writes that it"s important not to overlook "other factors that directly affect global health," such as roads and water and sanitation systems. He points to the U.S. government"s Millennium Challenge Corporation, which "takes a holistic approach to global health, laying the groundwork for poverty reduction and economic development.""By building healthier, hopeful, and productive communities, we build safer and more secure societies that can alleviate global poverty and contribute to global prosperity," Frist writes. "When communities are productive and thriving they don"t become breeding grounds for dangerous extremism" (Frist, Charlotte Observer, 5/14).
The NMC announced the appointment of Roger Thompson as its new Director of Standards and Registration.
Polio, or poliomyelitis, is a highly contagious viral infection that can lead to paralysis, breathing problems, or even death. The term poliomyelitis is from the Greek poliÃös meaning "grey", myelÃös referencing the spinal cord, and -itis meaning inflammation.
The Agency for Healthcare Research and Quality"s annual release of state-by-state quality data continues to give states mixed reviews for the quality of care they provide. As in previous years, AHRQ"s 2008 State Snapshots show that no state does well or poorly on all quality measures.
Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies. With regenerated cells, researchers hope to one day fill the acute shortage in pancreatic and liver tissue available for transplantation in cases of type I diabetes and acute liver failure.
Researchers from the Royal Adelaide Hospital and University of Adelaide believe our oldest mammalian relative may help us to better understand ovarian cancer.
According to the CDC"s (Center for Disease Control and Prevention"s) Friday evening weekly update, 27th June 2009, there have been 27,717 laboratory confirmed human cases including 127 deaths of Swine Flu or A(H1N1) influenza. Fortunately, so far the Swine Flu A(H1N1) virus appears to be no more virulent than ordinary seasonal human influenza. No reports have come in indicating that the virus may have mutated.
NPR began a series of reports on the health care lobbyists who attend Congressional sessions as part of their campaign. Richard Miller, a "longtime lobbyist for the American Chiropractic Association, says it"s important that the chiropractors keep on top of the health care overhaul legislation - and also take pains to make sure that senators and staff see them doing that, because the chiropractors are small dogs in a big fight." President Barack Obama "certainly sees Washington"s lobbyists as an obstacle to change. He"s tried limiting their access to the executive branch, but that runs into the constitutional question." Lobbying is on the rise: "Between 1998 and 2008, the number of registered lobbyists on health care more than doubled, to 3,627, according to the Center for Responsive Politics." Spending also increased: "Organizations lobbying on health care spent $484.4 million in 2008, more than two and a half times the spending in 1998." The project includes an interactive panoramic photo of lobbyists in the Senate HELP Committee hearing room and asks readers to help identify the players (Overby and Seabrook, 6/25).
As of January 2010, the Bulletin de la Sociç©tç© de Pathologie Exotique will join Springer"s publishing program. Founded in 1908 by Nobel Laureate Louis-Alphonse Laveran, the society celebrated its centenary last year. It plays a major role in the promotion of health issues and information on tropical pathology.
The Wall Street Journal reports that drug companies are increasingly using medical science liaisons: "Pharmaceutical companies are barred by the Food and Drug Administration from promoting unapproved drug uses, called off-label use, but they are using employees called "medical science liaisons," who are often physicians and pharmacists, as a legal way to discuss those uses. Medical science liaisons, who are considered medical rather than sales staff, have greater freedom than salespeople as they visit doctors offices to discuss the science behind a medicine, including unapproved uses." It notes: "The FDA requires traditional sales reps to refer information requests to their employers" medical or scientific staff, MSLs are usually on those staffs."
Five years from now, Lab scientists will be able to better determine how, when and why plutonium moves in soil and groundwater.
A clinical trial of masitinib, a drug in development for the treatment of rheumatoid arthritis, has shown it to be well tolerated and effective. Researchers writing in BioMed Central"s open access journal Arthritis Research and Therapy have shown that treatment with masitinib significantly reduced the severity of active arthritis.
No time to keep abreast of the most important osteoporosis-related research? Progress in Osteoporosis, the free online journal published by the International Osteoporosis Foundation (IOF) on http://www.iofbonehealth.org/pio provides concise summaries of new research published in the preceding three to four months. The journal is edited by leading osteoporosis researcher and author, Professor Ego Seeman of the University of Melbourne, Australia.
Staphylococcus epidermidis is quite an opportunist. Commonly found on human skin, the bacteria pose little danger. But S. epidermidis is a leading cause of infections in hospitals. From catheters to prosthetics, the bacteria are known to hitch a ride on a range of medical devices implanted into patients.
AIDS Vaccine Day, May 18, marks the occasion in 1997 when U.S. President Bill Clinton challenged researchers to come up with an AIDS vaccine within the following decade, stating that such a vaccine was the only way to eliminate the threat of AIDS. Twelve years later, the goal of an effective HIV vaccine remains unfulfilled, but the need for one remains urgent. AIDS is the number four killer in the world and number one in sub-Saharan Africa. Despite education and prevention campaigns, every day 7,500 people become infected with HIV. Antiretroviral drugs can prolong the lives of those who are infected, but they are not cures, and because of their cost and logistical difficulties, they reach only a minority of those who need them. And for every two individuals who go on antiretroviral treatment, five become HIV infected. As with any major viral pandemic, a vaccine remains the best hope of ending, and not just mitigating, AIDS.
Less than one-half of one percent (0.4%) of the 22 million people in the U.S. who are medically eligible for bariatric surgery actually get the surgery, and those who do are most likely to be white females with higher incomes and covered by private health insurance, according to a new study presented here at the 26th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS).
UCB announced that Neupro® (rotigotine transdermal patch) can now be prescribed to all patients with idiopathic Parkinson"s disease in Europe and is newly available for the symptomatic treatment of moderate to severe idiopathic Restless Legs Syndrome (RLS) in adults. This follows the decision of the European Commission to lift treatment restrictions on Neupro® in line with the recommendation of the European Medicines Agency (EMEA), issued on 29 May 2009.
Advance in detecting melamine-adulterated food
Experimental devices that read brain signals have helped paralyzed people use computers and may let amputees control bionic limbs. But existing devices use tiny electrodes that poke into the brain. Now, a University of Utah study shows that brain signals controlling arm movements can be detected accurately using new microelectrodes that sit on the brain but don"t penetrate it.
A groundbreaking non-invasive breast cancer treatment will be unveiled at this year"s Royal Society Summer Science Exhibition . Scientists led by world-renowned breast cancer expert, Mr Mo Keshtgar, are the first to use photodynamic therapy (PDT) to treat what is now the most common cancer in the UK.*
UCB announced that Neupro(R) (rotigotine transdermal patch) can now be prescribed to all patients with idiopathic Parkinson"s disease in Europe and is newly available for the symptomatic treatment of moderate to severe idiopathic Restless Legs Syndrome (RLS) in adults. This follows the decision of the European Commission to lift treatment restrictions on Neupro® in line with the recommendation of the European Medicines Agency (EMEA), issued on 29 May 2009.
New data show that surgeons can use USGI Medical Inc."s (USGI) Incisionless Operating Platform(TM) (IOP) to durably reduce the size of the stomach pouch and stoma in Roux-en-Y Gastric Bypass (RYGB) patients who are regaining weight because this portion of their anatomy has stretched since their original surgery.
DOR BioPharma, Inc. (DOR or the Company) (OTC Bulletin Board: DORB), a late-stage biopharmaceutical company, announced that investigators at the Fred Hutchinson Cancer Research Center, Seattle, Washington, published a paper this morning in Bone Marrow Transplantation in which they demonstrate that DOR"s lead product orBec(R) (oral beclomethasone dipropionate or BDP) decreases non-infectious inflammation of the lung in acute gastrointestinal Graft-versus-Host disease (GI GVHD) patients who received allogeneic hematopoietic cell transplants (HCT). Non-infectious inflammation of the lung is a common and potentially fatal complication of HCT that decreases the exchange of oxygen and carbon dioxide between the lung and blood and, in its severe form, may present as interstitial pneumonitis. The full article, entitled "Influence of Oral Beclomethasone Dipropionate on Early Non-Infectious Pulmonary Outcomes after Allogeneic Hematopoietic Cell Transplantation.
Vantia Therapeutics, an emerging pharmaceutical company developing novel, small molecule drugs targeting large, underserved medical markets, announces positive results from a Phase IIa clinical trial of its lead development compound VA106483 for nocturia. The trial showed that oral VA106483 was successful in producing a predictable and sustained anti-diuretic effect in patients, as determined by increased osmolality and decreased urine output. The study also found that VA106483 was generally well tolerated among the patient population.
Patients who have regained weight after gastric bypass surgery now have access to an incisionless procedure that appears highly effective at reversing weight gain, according to data presented at the annual meeting of the American Society of Metabolic and Bariatric Surgeons. Santiago Horgan, MD, professor of surgery and director of the Center for the Treatment of Obesity at UC San Diego, presented six-month outcomes from a national registry of 116 patients who underwent the procedure, known as ROSE (Restorative Obesity Surgery, Endolumenal).
Preventative Treatment Against Malaria May be Less Effective in Malnourished Children
In a leading medical journal this week US researchers describe the 90-year history of swine flu and warn about working with "freezer" viruses,
The odds of contracting mad cow disease from banned or adulterated bovine protein lurking in raw or processed food for humans or meat-bone meal for livestock have declined over the past decade. So have the risks of purchasing fishy imposters billed as red snapper, ground beef that isn"t all cow, or spoiled meat that doesn"t look or smell bad ò€¦ yet.
Specific variations or mutations in a particular can gene raise a man"s risk of familial, or inherited, testicular germ-cell cancer, the most common form of this disease, according to new research by scientists at the National Institutes of Health. This is only the second gene to be identified that affects the risk of familial testicular cancer, and the first gene in a key biochemical pathway. The study appears in the July 2009 Cancer Research.
A bill (S. 221) approved by the North Carolina Legislature that would require a public school sex education curriculum covering abstinence, contraception and sexually transmitted infections "will be the most comprehensive and science-based approach the state has used" for sex education, a Charlotte Observer editorial states, adding that Gov. Bev Perdue (D) "should sign it." The bill would require all public school districts in the state to teach a curriculum that focuses on abstinence but also includes information on preventing pregnancy and STIs. Parents would be able to have their children removed from the comprehensive portions of instruction. According to the editorial, the measure "still gives parents a choice in deciding what kind of sex education their children will receive." The editorial adds, "It also finally provides a curriculum that gives N.C. students vital access to age-appropriate, science-based information critical to their health, safety and well-being," which is "the kind of information that can help them make smart choices in serious situations."Parents are "often the best people for kids to turn to for advice and information" on sex, but "not all children have parents who can provide it, or are even willing to," and "not all children [who] go to their parents adhere to their advice," the editorial states. It continues, "The schools provide another avenue to get this critical advice and information -- and state lawmakers are right to make it available." According to the Observer, North Carolina has the ninth-highest teenage pregnancy rate in the U.S., and about "20,000 teenagers will get pregnant in North Carolina this year." A "comprehensive, science-based education program can help reduce the number of unintended teen pregnancies" and help reduce the spread of STIs, the editorial says. It concludes, "By reaching agreement on this matter, state lawmakers have given the children of this state vital tools to safeguard their health and welfare. ... Perdue should sign this bill and make it law" (Charlotte Observer, 6/26).
Newsweek Examines Efforts To Stop Disease Spread By Genetically Modifing Mosquitoes
A new report finds that "a growing global trade in black market cigarettes is killing tens of thousands of people a year, causing massive health problems and costing governments billions of pounds," the Guardian reports.
HIV diagnoses among all men in Louisiana declined from 1997 to 2006, but increased in 2007 and 2008 - diagnoses in the New Orleans metropolitan area alone increased by 9 percent from 2007 to 2008, according to the Louisiana Office of Public Health, the New Orleans Times Picayune reports. Of particular concern are the increases among black men in New Orleans. Among black men of all ages, new HIV diagnoses increased by 4 percent from 2007 to 2008, but increased 23 percent for black men age 20 to 24 and 30 percent for those age 45 to 54. The reasons behind the findings are "complex," according to the Times Picayune. Risky sexual behavior, a "declining sense of concern among young people about AIDS and the stubborn cultural stigma of homosexuality in the black community are all believed to be factors," the Times Picayune reports (Sandoval-Griffin, New Orleans Times Picayune, 6/27).
Mental health services could be improved by
A special monograph of the British Journal of Educational Psychology , published this month, highlights the very latest psychological research into the teaching and learning of writing.
Findings from Universitç© de Montrç©al"s Louis-H. Lafontaine Hospital-Fernand-Seguin Research Centre and McGill University Health Centre
University of Minnesota Medical School researcher Iris Borowsky, M.D., Ph.D., and colleagues found that one in seven adolescents believe that it is highly likely that they will die before age 35, and this belief predicted that the adolescents" would engage in risky behaviors.
Aside from the obvious and immediate health problems that patients undergoing mechanical ventilation face, those who recover often do so with profound loss of strength and mobility that can impair their daily functioning and even lead to increased risk of morbidity and mortality down the line. Now research shows that functional status may be restored earlier to ICU patients by performing daily interruptions in sedation paired with mobilization and exercise, as led by physical and occupational therapists.
The Australian Nursing Federation joined other unions in celebrating the end of WorkChoices.
Achaogen, a clinical stage biopharmaceutical company addressing the issue of multi-drug resistant bacterial infections through the discovery and development of innovative broad-spectrum antibiotics, announced today the presentation of research on aminoglycoside (AG) resistance trends and comparative AG toxicities at the 19th Annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), being held May 16-19, 2009 in Helsinki, Finland.
XCounter AB (publ) (AIM:XCT), a technology leader in the development of tomosynthesis-based 3D medical imaging, announced positive initial results from the first clinical evaluation of its innovative breast screening device XC Mammo - 3T. The device is the world"s first dedicated 3D digital mammography system for the detection of breast cancer, the most common form of cancer found in women.
Healthcare workers in South Africa are at a significantly increased risk of developing drug-resistant tuberculosis, or XDR-TB, in a trend which threatens to further exacerbate the already beleaguered healthcare systems in sub-Saharan countries, according to results of a new study. Researchers say the results underscore the urgent need for stringent TB screening policies among healthcare workers in these areas.
There is no way to know how the newest strain of the H1N1 influenza virus will behave in the future. But scientists, notably those working at the intersections of epidemiology, mathematics, modeling and statistics, are monitoring it closely to identify anomalies on its pattern of spread while evaluating ways of mitigating its impact.
The July issue of European Urology, the official journal of the European Association of Urology, features an editorial by Lars Holmberg comparing the results from the European Randomised Study of Screening for Prostate Cancer (ERSPC) with the results from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) In the editorial, Professor Holmberg writes that "The studies illustrate that the price to pay for 20% reduction in prostate cancer deaths is high; overdiagnosis and overtreatment are great problems. The answers lie in improving the PSA test or finding biomarkers that effectively separate aggressive cancers from slow-growing ones. We identify some priorities in the discussion about PSA testing."
The more than 1.5 million Americans with systemic lupus erythematosus (or lupus) suffer from a variety of symptoms that flare and subside, often including painful or swollen joints, extreme fatigue, skin rashes, fever, and kidney problems. Researchers at The Scripps Research Institute have now identified the main trigger for the development of this disease.
Abnormal levels of trace elements may explain dialysis morbidity. A systematic review published in the open access journal BMC Medicine has shown that, compared to healthy controls, dialysis patients have significantly different blood concentrations of trace elements.
The Body Benchmark Study was launched in March 2007, with the goal of developing the Body Volume Index (BVI) as a potential long-term replacement for the Body Mass Index (BMI) for the measurement of obesity and associated health risks. Now, the latest results in the ongoing research aimed at validating its use in a medical context are showing more accuracy than results from using a tape measure.
Cephalon, Inc. (Nasdaq: CEPH) announced that it has submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) requesting approval of NUVIGIL(R) (armodafinil) Tablets [C-IV] for the indication of improved wakefulness in patients with excessive sleepiness associated with jet lag disorder resulting from eastbound travel. Jet lag disorder is an acute condition that occurs when a person"s internal body clock becomes disrupted as a result of rapid travel across several time zones. Based on U.S. Bureau of Labor Statistics findings, an estimated 70 million American travelers experience jet lag annually. Currently, there are no FDA-approved medications to improve wakefulness in travelers who experience the excessive sleepiness commonly associated with long flights.
Roche, the maker of ACCU-CHEK blood glucose monitoring systems and insulin pumps, announced today the latest component of its Behavior Change through Patient Engagement (sm) program. Creative Coaching is an advanced educational program that fights the growing epidemic of diabetes by improving dialogue between diabetes educators and their patients.
An article published Online First and in a future edition of The Lancet reports on the use of Ketamine as a safe and valuable substitute to conventional etomidate. It is used as a sedative during intubation. Critically ill patients frequently require tubing inserted into their airways to help control their breathing during treatment. The article is the work of Professor Frederic Adnet, SAMU 93, of the Hç´pitaux de Paris, France, and his team.
Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) and its partner, Antares Pharma, Inc. (NYSE Amex: AIS) announced the approval of a Supplemental New Drug Application (sNDA), which added "needle-free injection" to its Tev-Tropin® [somatropin (rDNA) for injection] brand human growth hormone (hGH) drug label. Teva will market the Antares needle-free device as the Tev-Tropin Tjet Injector system.
Two recent advancements in ovarian transplant techniques could potentially expand the availability of the procedure for women seeking to avoid fertility problems as they age, researchers reported Monday at a meeting of the European Society of Human Reproduction and Embryology, the AP/Yahoo! News reports. According to the AP/Yahoo! News, ovary transplants traditionally have been performed on women with cancer as a method of preserving fertility after chemotherapy or other treatments that can affect the reproductive system. The procedure involves removing the ovaries before treatment and re-implanting them after treatment is complete. Because only a handful of these procedures have been successful, ovarian transplants have been an option only for women with serious diseases. However, as more women delay having children until their 30s or 40s, researchers say the new techniques, in theory, could make it simpler for healthy younger women to have an ovary removed, frozen and then re-implanted later in life when they are ready to have children.The first study examined how many eggs were lost or preserved in fresh and frozen ovarian tissue of 15 young women prior to the start of cancer treatment. According to the study, there was no difference in the quantity of eggs in the fresh tissue and in the ovaries frozen using a new ultra-fast technique. The study found that about 50% of a woman"s eggs were lost using the traditional, slow-freezing methods of preserving the ovaries.The second study reported on a new surgical technique to restore an ovary"s function after transplantation. For the study, Pascal Piver of Limoges University Hospital and colleagues divided the transplant process into two separate procedures in an attempt to more quickly re-establish blood and hormone supplies to the ovary. In the first procedure, the researchers performed a graft of small pieces of ovarian tissue to prompt blood vessels to grow. They performed the ovary transplant three days later. The technique was successful in a woman who lost fertility because of treatment for sickle cell anemia.Sherman Silber, director of the St. Louis Infertility Center in Missouri and a researcher for the first study, said the new techniques "could dramatically expand our reproductive life span." He added, "This is not an experimental procedure for cancer patients anymore. The question is whether more women should be able to have this option" (Cheng, AP/Yahoo! News, 6/29).
"Lawmakers working to overhaul the U.S. health-care system face a pressure-filled July after leaving town this week without resolving the biggest questions dividing Democrats and Republicans," Bloomberg reports. Democrats on the Senate Finance Committee - which observers deem most likely to come up with a passable, bipartisan bill - have been working to reduce the cost of the overhaul to gain Republican support, but had not yet released a proposal. Bloomberg adds: "While the Congressional Budget Office said options under consideration by the committee can keep the cost within Baucus"s goal of $1 trillion over 10 years, how to pay for the plan remains unsettled. So is structuring some kind of government-run competition for insurers. ... "Nothing has been set," Montana Democrat [Max] Baucus told reporters in the Capitol on June 25. The recess offers a chance for "taking stock," he said" (Jensen and Livkin, 6/29).
"Much of the TV advertising on health care so far has focused on the controversial public, or government-run insurance program that Democrats say would compete with private insurers and Republicans say would drive them out of business," but the Laborers" International Union of North America "will begin airing ads in two states Tuesday that deal with an equally explosive issue: Taxing health benefits," USA Today reports. The union will "run the ads at least through Thursday in North Dakota and Montana," home states of "the two most important senators on the issue, Senate Finance Chairman Max Baucus, D-Mont., and Senate Budget Committee Chairman Kent Conrad, D-N.D." The ads reveal the "fine line labor is walking" on health care: "The ads first praise Congress for taking up the health care debate but then criticize an idea that could be included in one draft of the legislation to tax health care premiums" (Fritze, 6/29).
Dr. Gary D. Kao testified Monday about botched prostate cancer treatment he gave to patients at a Veterans Affairs hospital run by the University of Pennsylvania. The New York Times reports: "The radiation oncologist whom regulators accuse of mishandling scores of radioactive seed implants at the Philadelphia veterans" hospital told a Congressional panel on Monday that while he "could have done better" with some implants, his patients over all received effective treatment for their prostrate cancer."
The National Pharmacy Association (NPA) and Allergy UK are offering the community pharmacy allergy screening service to members of the public attending the Hampton Court Palace Flower Show from 7 July to 12 July.
Katherine Camacho Carr, CNM, PhD, a certified nurse-midwife, professor and assistant dean of graduate studies at the Seattle University College of Nursing, is the recipient of the 2009 Hattie Hemschemeyer Award from the American College of Nurse-Midwives (ACNM.) The "Hattie" is ACNM"s most prestigious award and was presented to Carr at ACNM"s 54th Annual Meeting in Seattle. Carr has been a resident of the Seattle area for 32 years.
Researchers at North Carolina State University and the Georgia Institute of Technology have received a $1.2 million grant from the National Science Foundation to study whether and how video games can boost memory and thinking skills in the elderly - and then to use their findings to develop a prototype video game to do just that.
Elsevier, the leading publisher of scientific, technical and medical information, is pleased to announce its renewed publishing partnership with The European Association for the Study of the Liver (EASL), the leading European association in the field of liver research. The agreement calls for Elsevier to publish the society"s flagship journal, the Journal of Hepatology, for the next five years.
One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis.
A major new trial recently published in the journal Fertility and Sterility shows that for couples beginning infertility treatments, an accelerated path to in-vitro fertilization (IVF) can offer a shorter time to pregnancy, cost savings of nearly $10,000, and a lowered risk of multiple births.
While major advances have been made in the understanding of posterior cruciate ligament (PCL) anatomy and reconstruction, a literature review published in the July 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS) finds that there must be continued advances in basic science research in order to determine the best course of treatment for those with PCL injuries.
The equipment used for biomedical research is shrinking, but the physical properties of the fluids under investigation are not changing. This creates a problem: the reservoirs that hold the liquid are now so small that forces between molecules on the liquid"s surface dominate, and one can no longer shake the container to mix two fluids. Instead, researchers must bide their time and wait for diffusion to occur.
Tuberculosis (TB) is a difficult infection to treat and requires six months of multiple antibiotics to cure it. To combat the TB pandemic, a shorter and simpler drug treatment would be a huge advance since most TB occurs in re-limited settings with poor public health infrastructures.
Throwing "swine flu parties" in an attempt to get immunity against the virus while it is a fairly mild form is not a good idea, the BMA said yesterday, 1 July 2009.
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced results from a Phase 3b study that found VYVANSE® (lisdexamfetamine dimesylate) CII demonstrated significant efficacy at 14 hours after administration during a simulated workplace environment study in adults with Attention Deficit Hyperactivity Disorder (ADHD). VYVANSE is the first approved stimulant for adults with ADHD to be evaluated in this setting, and these data were presented today at the 49th annual New Clinical Drug Evaluation Unit meeting in Hollywood, FL. VYVANSE is currently approved by the US Food and Drug Administration (FDA) for the treatment of ADHD in children age 6 to 12 years and in adults with ADHD.
Diabetics undergoing total joint replacement often are at a higher risk of experiencing complications after surgery due to various pre-existing health conditions. According to a new study published in the July 2009 issue of The Journal of Bone and Joint Surgery (JBJS), those complications are less likely to occur when a diabetic patient has glucose levels under control.
One of the most controversial issues in men"s health is whether men should routinely have a blood test for prostate-specific antigen (PSA) to screen for prostate cancer. Some experts argue that PSA testing saves lives by helping detect this common form of cancer early. Others say it triggers unnecessary treatment that disrupts many more lives than it saves. The results of two studies released this spring focused the debate, but scientists are still a long way from concluding the discussion, reports the July 2009 issue of Harvard Men"s Health Watch.
On June 11, the National Institute for Health and Clinical Excellence
In a first-of-its-kind advance toward the next generation of genetically modified foods - intended to improve consumers" health - researchers in Japan are reporting that a new transgenic rice designed to fight a common pollen allergy appears safe in animal studies. Their report is in the current issue of ACS" Journal of Agricultural and Food Chemistry, a bi-weekly publication.
Traumatic Brain Injury (TBI) is the single most common cause of death and disability in children and adolescents, according to the Centers for Disease Control. Now, according to a new study by UCLA researchers, the effects of a blow to the head, whether it"s mild or a concussion, can linger for years.
UCB announced that the U.S. Food and Drug Administration (FDA) approved Cimzia®, the only PEGylated anti-TNF (Tumor Necrosis Factor), for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA). Cimzia® can be dosed at 400 mg initially and at weeks two and four, followed by 200 mg every other week; for maintenance dosing, 400 mg every four weeks can be considered.
HIV-Positive Babies More Likely To Contract Deadly TB If Given BCG
In this months editorial the Editors argue that-despite recent international objections- access to clean water should be recognised as a human
In the coming summer months it is estimated that 200,000 young people in Europe will become infected with Chlamydia and most of them won"t know that they are infected. Chlamydia trachomatis, the most common bacterial sexually transmitted infection in Europe, continues to increase in many countries. It affects mostly young adults under 25. The true occurrence of Chlamydia is most likely much higher than the official figures because the majority of the infected do not have clinical symptoms. Surveys in European countries have shown an estimated population prevalence of 5 to 10 % in young people.
The U.S. should conduct research to compare the effectiveness of innovative programs aimed at preventing unintended pregnancy, according to a report issued Tuesday by a congressionally convened Institute of Medicine panel, the New York Times reports (Meier, New York Times, 7/1). The recommendations state that these strategies should include "over-the-counter access to oral contraceptives or other hormonal methods, expanding access to long-acting methods for young women, [and] providing free contraceptive methods at public clinics, pharmacies or other locations" (List of Priorities, IOM, 6/26). The report lists 100 health topics that should be prioritized as the Obama administration seeks to increase cost-effectiveness in medicine. The federal stimulus package passed earlier this year allotted $1.1 billion for comparative effectiveness research into different ways of treating certain conditions and addressing various health care issues. According to the Times, the report is a first step in an expansive effort by the administration and health experts to direct medical practice toward scientifically proven treatments, rather than a provider"s personal opinion or a medical product company"s promotional claims. Harold Sox, co-chair of the IOM panel that wrote the report and the editor of the Annals of Internal Medicine, said that based on public comments, the panel decided it was important to include pregnancy prevention and other public health issues in its recommendations (Meier, New York Times, 7/1). The report also recommends that researchers compare different comprehensive care coordination programs, such as the medical home model and chronic disease management, especially in communities known to have health disparities (Simmons, HealthLeaders Media, 6/30).
Mental health charity Mind has announced that Times journalist Sathnam Sanghera has won this year"s Mind Book of the Year Award for "The Boy with the Topknot: a memoir of love, secrets and lies in Wolverhampton" (1). The memoir is about growing up in Wolverhampton and retrospectively discovering at the age of 24 that both his father and sister had schizophrenia.
Michigan from 1992 to 2007 experienced improvements in rates of teenage pregnancies, smoking among pregnant women, and six other indicators of maternal and infant health, though there was an increase in out-of-wedlock births and low-birthweight infants, according to a Michigan League for Human Services report issued Tuesday, the Detroit News reports. The report, titled "Right Start in Michigan," examined statistics in eight categories that affect the health of newborns. The findings track trends for the state as a whole and for its 83 counties and 69 communities with populations greater than 25,000 (Jun, Detroit News, 6/30). According to the report, teen births and repeat births decreased by more than 25% statewide (AP/9and10news.com, 6/30). The decline in teen births was more pronounced in urban areas (Lavey, Lansing State Journal, 6/30). The report also found that the rate of women who received no or late prenatal care dropped by 15%, while the rate of premature births declined by 9%. In addition, smoking by pregnant women decreased by more than one-third. However, out-of-wedlock births increased by 10%, and the percentage of low-birthweight infants rose by 10% (AP/9and10news.com, 6/30).State budget cuts are expected to affect assistance programs for teen and low-income women with children, according to the Lansing State Journal. Marcus Cheatham, assistant deputy health officer for Ingham County, Mich., said, "I"m really worried that we"re going to lose the gains we"ve made in this state" (Lansing State Journal, 6/30).
Alastair Campbell has won Mind"s Champion of the Year Award for his significant contribution to raising awareness of mental health. He beat fellow nominee and chat show host Paul O"Grady, among other mental health campaigners, to the prestigious award announced yesterday evening.
Medicaid receives increased attention while an underused, special monthly pension benefit called Aid and Attendance can help veterans, and spouses, with assisted living.
The University of Queensland will establish a $2.5million GP Super Clinic at Ipswich that will focus on key local health issues.
The Australian Medical Students" Association (AMSA) Global Health Conference continues today, with the focus turning towards our own backyard.
Sucampo Pharma Americas, Inc., a wholly owned subsidiary of Sucampo Pharmaceuticals, Inc. (NASDAQ:SCMP), today reported top-line results from its phase 2 clinical trial of orally administered cobiprostone for the prevention of gastric ulcers and other gastrointestinal injuries in patients treated with non-steroidal anti-inflammatory drugs (NSAIDs).
Stanford University School of Medicine scientists have played a major role in an international effort that has shown, for the first time, that modern genetic technologies can solve the riddle of how gene variations lead to schizophrenia.
Governor M. Jodi Rell announced that the State of Connecticut is receiving $3.75 million federal grant to expand access to health care in Hartford for low-income women nearing childbirth to ensure their newborns get a healthy start.
For years, genes have been considered the one and only way biological traits could be passed down through generations of organisms.
The salamander is a superhero of regeneration, able to replace lost limbs, damaged lungs, sliced spinal cord -- even bits of lopped-off brain.
The largest study to date of endometriosis in pregnant women has found that the condition is a major risk factor for premature birth, the 25th annual conference of the European Society of Human Reproduction and Embryology heard. Dr. Henrik Falconer, of the Department of Woman and Child Health, Karolinska Institute, Stockholm, Sweden, said that his team had found that women with endometriosis also had a higher risk of other pregnancy complications, as well as being more likely to give birth through Caesarean section. The research is published on-line in the journal Human Reproduction*.
Stanford University School of Medicine scientists have played a major role in an international effort that has shown, for the first time, that modern genetic technologies can solve the riddle of how gene variations lead to schizophrenia.
Even under favorable assumptions, including lifelong protection against 70% of all cervical cancers and no side effects, vaccination against the human papillomavirus (HPV) is not cost-effective in the Netherlands, according to a study published online July 1 in the Journal of the National Cancer Institute.
New research, conducted by Charles Wingo and his colleagues, at the University of Florida, Gainsville, suggests a link between the circadian rhythm and control of sodium (salt) levels in mice.
A study in the July 1 issue of the journal SLEEP suggests that postpartum depression may aggravate an already impaired sleep quality, as experiencing difficulties with sleep is a symptom of depression. Twenty-one percent of depressed postpartum women included in the study reported having also been depressed during pregnancy and 46 percent reported at least one previous depressive episode prior to conception, suggesting that new mothers diagnosed with postpartum depression are not merely reporting symptoms of chronic sleep deprivation.
Closing residential homes affects quality of life.
Tekmira Pharmaceuticals Corporation (TSX:TKM) announced that it has initiated a Phase 1 human clinical trial for ApoB SNALP. ApoB SNALP, Tekmira"s lead RNAi therapeutic product candidate, is being developed as a treatment for patients with elevated low-density lipoprotein (LDL) cholesterol, or "bad" cholesterol, who are not well served by current therapy. ApoB SNALP is designed to reduce the production of apolipoprotein B (ApoB), a protein produced in the liver that plays a central role in cholesterol metabolism.
Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced that the U.S. Food and Drug Administration (FDA) has approved Multaq(R) (dronedarone) 400 mg Tablets. Patients with atrial fibrillation (AF) or atrial flutter (AFL) soon will have a new treatment option to help improve current management of their disease. Multaq(R) is the first drug approved in the United States that has shown a clinical benefit to reduce cardiovascular hospitalization in patients with AF/AFL.
Some Iowa groups are concerned that the state"s criminal HIV transmission law adds to the stigma associated with the virus and hampers testing efforts, and are urging lawmakers to revisit the law, the Iowa Independent reports. According to the Independent, criminal transmission of HIV is classified among the second-most serious felonies that can be committed in the state. Those that have been convicted under the law have been sentenced to a few months to several decades in prison. Former state Rep. Ed Fallon (D) who supported the 1998 law, said, "It seems to me that since it is now 11, almost 12, years later, it wouldn"t be [a] bad time to take a look at it again," adding that "surely [there] are some tweaks or changes that the legislature could consider relevant to this law, especially with all the new knowledge we have of the disease" (Waddington, 7/1).
-- 34 confirmed cases in Wales, with 4 new cases:
The Wall Street Journal examines how some U.S.-based health care programs are improving their treatment capabilities by learning from strategies used in developing countries. "When doctors running the AIDS clinic at the University of Alabama at Birmingham wanted to increase the number of patients who showed up for treatment, they turned to an unusual place for help: southern Africa," Wall Street Journal writes. By using an AIDS clinic in Zambia as a model, the Alabama clinic was able to decrease its no-show rate "from 31% in 2007 to 18% through June 2009."
In an effort to encourage medical professionals to provide services to low-income rural populations in India, Union Health and Family Welfare Minister Ghulam Nabi Azad announced an initiative that will significantly raise the salary of "doctors, specialists and para-medical staff" who elect to work in "rural, particularly far-flung and inaccessible areas," the Hindu reports.
"A year into a new effort to expand health coverage, recession-weary Marylanders are flocking to the state"s Medicaid program in numbers far greater than expected, costing the state $50 million more in the process," The Baltimore Sun reports. "As of this week, 44,255 additional state residents had enrolled in Maryland"s Medicaid system after income limits were significantly relaxed, outpacing projections that enrollment would increase by 26,605." Health advocates say "the state is doing the right thing by expanding publicly funded health care to adults who have children," but "increased enrollment has also enlarged the price tag." And "while the federal government picks up half the cost, the higher expenses come as Maryland is battling severe budget shortfalls. State health spending has been propped up this year by a major influx of stimulus dollars. Proponents had hoped to extend the public plan to adults without children this year, but the initiative was a victim of state budget constraints" (Fisher, 7/2).
The following summarizes news coverage of state abortion statistics in Minnesota and Wisconsin.~ Minnesota: The number of abortions performed in Minnesota decreased for the second consecutive year in 2008, according to an annual report from the state Department of Health, the Minneapolis Star Tribune reports. Except for a one-time increase in 2006, the number of abortions in Minnesota has trended downward since a peak in 1980, when 19,028 procedures were performed. The new report found that 12,948 abortions were performed in the state in 2008, a decrease of 895 from 2007. Women ages 20 to 24 accounted for about one-third of the procedures, the most among any age group. The number of procedures among teenagers continued a decline that began in the 1990s but had leveled off slightly earlier this decade, the report found. The report also found that less than one-third of women reported using contraception and about one in seven was married at the time of conception (Von Sternberg, Minneapolis Star Tribune, 7/1).~ Wisconsin: Wisconsin abortion providers performed 8,229 procedures in 2008, the lowest number since the state began collecting statistics in 1974, according to an annual report by the state Department of Health Services, the AP/Milwaukee Journal-Sentinel reports. The number of abortions has declined annually since 2003, when 10,557 procedures were performed. State law requires abortion providers to provide DHS with the data. According to the report, slightly more than half of abortions took place in the first eight weeks of pregnancy. Women who had never been married accounted for about three-fourths of all procedures. The report found that 12% of abortions occurred among women ages 35 and older; 34% were among women ages 20 to 24; 11% were among women ages 18 and 19; and 6% were among girls ages 15 to 17. The number of abortions among minors decreased from 551 in 2007 to 500 in 2008, with parents providing consent in 452 of those cases (Richmond, AP/Milwaukee Journal-Sentinel, 6/30).
Over-the-counter remedies for menopause symptoms are growing in popularity among some women who fear potential risks from prescription hormone replacement therapy, the New York Times reports. According to the Times, the market for alternative therapies -- such as natural supplements and topical creams -- jumped in 2002 after initial results from the Women"s Health Initiative suggested that HRT could increase risk for heart disease, cancer, stroke and blood clots. Gynecologists estimate that about one-third of menopausal women are treated with conventional prescription hormones, and about one-third are treated with bio-identical hormones -- plant-derived synthetic hormones that mimic the molecular structure of human hormones. The remaining one-third either do not seek therapy for symptoms, are not bothered by symptoms or use over-the-counter therapies. There are more than 500 over-the-counter products available that claim to alleviate menopause symptoms, the Times reports. The treatments include such products as teas, low-dose progesterone creams, black cohosh capsules and phytoestrogens derived from soy and red clover, according to the Times. According to Nutrition Business Journal, the U.S. dietary supplement market associated with menopause increased from $211 million in 1999 to $337 million in 2007.Some studies have raised doubts about the safety and effectiveness of the over-the-counter remedies. Todd Cooperman -- director of consumerLab.com, a private nutrition product-testing lab -- said that his company"s study of more than one dozen products found that five failed to gain the lab"s approval because of problems such as inaccurate labeling or tainted ingredients. The Center for Botanical Dietary Supplements Research this fall is expected to release the results of a study, sponsored by the National Institutes of Health, that aims to determine the efficacy of the ingredients associated with menopause symptom relief. Some studies have questioned the efficacy of progesterone creams, which some experts contend can gather in fat cells and disrupt the production and synthesis of other hormones. Other experts maintain that the products are safe if properly used. Theresa Ramsey, director of the Center for Natural Healing in Arizona, said, "I think over all these products are generally safe, but must be taken in the right circumstances and in conjunction with a mindfully healthy approach to life if they are going to be effective at all" (Sweeney, New York Times, 7/2).
The opening of a unique centre will put Newcastle at the forefront of cancer research and bring benefits to patients in the North East.
We swim in a sea of information, but filter out most of what we see or hear. New analysis of data from dozens of studies sheds new light on how we choose what we do and do not hear. The study found that while people tend to avoid information that contradicts what they already think or believe, certain factors can cause them to seek out, or at least consider, other points of view.
Statement of Captain Charles D. Connor, U.S. Navy (Ret.), American Lung Association President and CEO: