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Bio-Inspired Cilia Mix Medical Reagents At Small Scales
The equipment used for biomedical research is shrinking, but the physical properties of the fluids under investigation are not changing. This creates a problem: the reservoirs that hold the liquid are now so small that forces between molecules on the liquid"s surface dominate, and one can no longer shake the container to mix two fluids. Instead, researchers must bide their time and wait for diffusion to occur.
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State Medicaid Coverage, Costs Grow In Maryland, Mississippi
"A year into a new effort to expand health coverage, recession-weary Marylanders are flocking to the state"s Medicaid program in numbers far greater than expected, costing the state $50 million more in the process," The Baltimore Sun reports. "As of this week, 44,255 additional state residents had enrolled in Maryland"s Medicaid system after income limits were significantly relaxed, outpacing projections that enrollment would increase by 26,605." Health advocates say "the state is doing the right thing by expanding publicly funded health care to adults who have children," but "increased enrollment has also enlarged the price tag." And "while the federal government picks up half the cost, the higher expenses come as Maryland is battling severe budget shortfalls. State health spending has been propped up this year by a major influx of stimulus dollars. Proponents had hoped to extend the public plan to adults without children this year, but the initiative was a victim of state budget constraints" (Fisher, 7/2).
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BioSante Pharmaceuticals Comments On Benefits Of Testosterone Use In HIV-Infected Women
BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX), which is developing a testosterone gel (LibiGel®) for the treatment of hypoactive sexual desire disorder (HSDD) in menopausal women, today commented on a paper published in the May 15, 2009 issue of AIDS, the Journal of the International AIDS Society, on the effect of testosterone in women infected with HIV. The peer-reviewed journal reported results of a randomized, placebo-controlled trial of testosterone in HIV-infected women indicating that long-term testosterone administration was well tolerated in HIV-infected women and resulted in significant improvement in body composition, bone mineral density (BMD), and quality of life indices.
Diagnostics

Using Ultrasound To Detect Early Signs Of Osteoarthritis

Researchers at The University of Nottingham are hoping to find out if inflammation of the knee could be an early sign of osteoarthritis - a condition which leads to pain, stiffness, swelling and disability. Up to six million people in the UK suffer from osteoarthritis in the knee. Now 200 patients, over the age of 55, from GP practices across Nottingham are to take part in a study led by research physiotherapist Michelle Hall in the School of Nursing, Midwifery and Physiotherapy. Mrs Hall, who is a lecturer in the Division of Physiotherapy Education, said: "It has been shown that people who have inflammation may develop more severe and progressive osteoarthritis and experience greater pain and disability. The ability to detect the presence of inflammation using Ultrasound could therefore be important in terms of prognosis and selection of certain treatments." With a three-year training fellowship from the Arthritis Research Campaign of ÷£192,000 Mrs Hall will use new ultrasound techniques to identify if this common condition, in people over 55, can be linked to osteoarthritis. At the moment osteoarthritis can only be identified by x-ray, which is limited to revealing changes to bones and degeneration of cartilage. It does not show up any changes or inflammation to the surrounding soft tissue or joint lining. This inflammation may also contribute to pain and stiffness and could, in fact, be a precursor to osteoarthritis. Osteoarthritis is known as a "wear and tear" condition in which cartilage wears away, leaving bones rubbing together. Recently scientists have shown that inflammation in the joint lining may also play a role in its development. The team from The University of Nottingham"s physiotherapy education and academic rheumatology departments aim to find out if people with knee pain and/or knee osteoarthritis also have inflammation in their knees. Patients will attend the Clinical Sciences Building at the University for the ultrasound scans which will repeated three months later or if participants report a change in their knee pain, to chart the progress of the inflammation to see whether this correlates with x-ray changes or with increases in pain. A control group of healthy volunteers will also undergo ultrasound on their knees as a comparison group. Michelle Hall University of Nottingham


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