Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Popular Articles

Heatwave Plan Updated With Advice For Those With Respiratory Problems, England
The Heatwave Plan has been updated to advise those suffering breathing problems that although ozone levels increase in hot weather, they drop in the evening. People with respiratory problems should stay inside during the hottest part of the day and windows should be kept shaded and closed when the temperature is hotter outside than inside.
generic viagra online
IDF To Host Clinical And Educational Workshops On Diabetes For Health And Government Officials In Latin America
The International
News of the day
World's Largest Bariatric Surgery Patient Database Exceeding 120,000 Patients Will Support Best Practices Development
Surgical Review Corporation (SRC), an independent, non-profit organization that advances the efficacy, efficiency and safety of bariatric and metabolic surgery, announced that the number of registered patients entered into its Bariatric Outcomes Longitudinal Database™ (BOLD™) has now surpassed 120,000. BOLD, the world"s largest dedicated repository of bariatric surgery patient information, provides the mechanism for identifying risk factors and quality indicators, developing risk stratification guidelines, and enabling continuous quality improvement for bariatric surgery.
Nutrition

Theratechnologies Presents Results From A Pharmacokinetic/Phamacodynamic Evaluation Of Tesamorelin At The Endocrine Society's Annual Meeting

Theratechnologies (TSX:TH) announced today that results from a pharmacokinetic/pharmacodynamic (PK/PD) evaluation of tesamorelin were presented as a poster (Poster number: P3-641) at the Endocrine Society"s 91st Annual Meeting in Washington D.C. Tesamorelin is an analogue of the growth hormone releasing factor evaluated for the treatment of excess abdominal fat in HIV patients with lipodystrophy. The poster outlined the results of two Phase 1 studies performed to determine the PK/PD profiles of tesamorelin after single and multiple administrations of 2 mg of tesamorelin once daily for 14 consecutive days, in healthy volunteers and HIV-positive patients receiving a stable antiretroviral regimen. The results showed that tesamorelin"s PK/PD profiles were generally similar in both groups and suggest that there is a minimal impact on tesamorelin"s PK parameters and on the induction of the insulin-like growth factor (IGF-1) when tesamorelin is given to HIV-positive patients on antiretroviral therapy. Levels of IGF-1 at baseline were within normal range and comparable in both groups (healthy: 175 ng/mL; HIV+: 164 ng/mL). After 14 days of daily injection, a similar increase was observed in healthy volunteers and in HIV-positive patients (115% and 121%, respectively, compared to baseline). In both studies, the extent of absorption (AUC) and the maximal concentration (Cmax) were similar (approximately 700 pgò€¢h/mL and 2400 pg/ml for AUC and Cmax, respectively). The half-life of tesamorelin ranged between 13 to 38 minutes in both healthy volunteers and HIV-positive patients. The poster presented is now available on Theratechnologies" website at http://www.theratech.com About HIV-Associated Lipodystrophy Several factors including the antiretroviral drug regimen and the virus itself are thought to contribute to HIV-associated lipodystrophy, which is characterized by body composition changes, dyslipidemia and glucose intolerance. The changes in body composition include excess abdominal fat accumulation. There is currently no approved treatment available for the excess abdominal fat related to HIV-associated lipodystrophy, a condition that can stigmatize patients and discourage HIV treatment adherence. Theratechnologies


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009