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FDA Approves Expanded Use Of ISENTRESS® (raltegravir) In Combination Therapy For Adult Patients With HIV-1 Infection
Merck & Co., Inc. announced that the U.S. Food and Drug Administration (FDA) has approved an expanded indication for ISENTRESS®. The broadened indication now includes use in the treatment of adult patients starting HIV-1 therapy for the first time (treatment-naïve), as well as in treatment-experienced adult patients. ISENTRESS is used in combination with other antiretroviral (ARV) medicines for the treatment of HIV-1 infection in adult patients. The indication for ISENTRESS is based on analyses of plasma HIV-1 RNA levels through 48 weeks in three double-blind controlled studies. Two of these studies were conducted in clinically advanced, 3-class antiretroviral (NNRT, NRTI, PI) treatment-experienced adults and one was conducted in treatment-naïve adults. The safety and efficacy of ISENTRESS have not been established in pediatric patients. The use of other active agents with ISENTRESS is associated with a greater likelihood of treatment response.
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Cayenne Medical Launches CrossFix™ System For Repair Of Meniscal Tears
Cayenne Medical, Inc., a privately held sports medicine company based in Scottsdale, announced the commercial launch of its CrossFix™ System for the repair of meniscal tears at the American Orthopaedic Society for Sports Medicine (AOSSM) annual meeting in Keystone, Colorado last week.
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Exploring The 'Ecosystems' Of Influenzas
Predicting the infection patterns of influenzas requires tracking both the ecology and the evolution of the fast-morphing viruses that cause them, said a Duke University researcher who enlists computers to model such changes.
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Study Finds Cogent's Hospitalist Programs Result In Profoundly Low Hospital Readmission Rates

Hospitalist programs designed and managed by Cogent Healthcare have been found by a recent academic study to have exceptionally low readmission rates, especially for Medicare patients, officials announced today. These results were found through a study co-authored by researchers from the University of Wisconsin and Northwestern University. Presented at the Society of Hospital Medicine"s Annual Meeting in May, the study findings were among those awarded Best of Research, Innovations and Clinical Vignettes. According to the study, which reviewed patients discharged from 25 hospitals in 11 states during a one year period, Medicare patients who had been treated and discharged from hospitalist programs - managed by Cogent teams and discharged home - were readmitted to study hospitals at a rate of only 6.4 percent within 30 days of discharge. Spotlight on Readmission Rates These findings come on the heels of important research published in the April 2009 issue of New England Journal of Medicine (NEJM) - "Rehospitalizations among Patients in the Medicare Fee-for-Service Program." The NEJM study has been featured frequently in national and trade press due to its impact on the current debate around national healthcare reform. The NEJM study analyzed national Medicare readmission data and found that approximately one-fifth or 20 percent of Medicare beneficiaries are rehospitalized within 30 days of discharge - costing Medicare $15 billion annually. Mark Williams, M.D., the Chief of the Division of Hospital Medicine at Northwestern University, was an author on both the NEJM study and on the Cogent study. Cogent"s System of Care "The results of the Cogent study demonstrate the value that Cogent brings to our hospital partners. Above all, we are committed to accountability, efficiency and providing consistent, high-quality care and service each patient receives during - and after - their hospital stay," said Ron Greeno, M.D., founder and Chief Medical Officer of Cogent. "We at Cogent feel our success in being able to prevent readmissions is directly attributable to the System of Care that is the hallmark of our programs." Unique to the company, Cogent"s System of Care supports hospitalists in the delivery of inpatient care, and includes significant infrastructure, a coordinated care team, data driven processes, rigorous ongoing training, experienced leadership and a standardized, patient-centric discharge process. That discharge process specifically includes: - Education provided to the patient and family prior to discharge, which reinforces the discharge plan and schedules a follow-up appointment. This education is led by the Cogent Care Team and provided in coordination with hospital personnel. - A "Homecoming Call" within 48 hours to review the patient"s medications and discharge plan. Any complications are relayed to the patient"s Cogent Care Team for follow-up and intervention. - Identification of high risk patients that may require special arrangements to help avoid hospital readmission. "As policymakers in Washington currently seek a solution for the broken U.S. healthcare delivery system, much emphasis is being placed on the need for improving efficiency and quality, and specifically reducing readmission rates," said Greeno. "These findings clearly demonstrate how hospital medicine, in particular the Cogent model of care, can meet these goals." Cogent Healthcare


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