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DOR BioPharma Announces Publication Of OrBec(R) Clinical Pulmonary Data In Bone Marrow Transplantation
DOR BioPharma, Inc. (DOR or the Company) (OTC Bulletin Board: DORB), a late-stage biopharmaceutical company, announced that investigators at the Fred Hutchinson Cancer Research Center, Seattle, Washington, published a paper this morning in Bone Marrow Transplantation in which they demonstrate that DOR"s lead product orBec(R) (oral beclomethasone dipropionate or BDP) decreases non-infectious inflammation of the lung in acute gastrointestinal Graft-versus-Host disease (GI GVHD) patients who received allogeneic hematopoietic cell transplants (HCT). Non-infectious inflammation of the lung is a common and potentially fatal complication of HCT that decreases the exchange of oxygen and carbon dioxide between the lung and blood and, in its severe form, may present as interstitial pneumonitis. The full article, entitled "Influence of Oral Beclomethasone Dipropionate on Early Non-Infectious Pulmonary Outcomes after Allogeneic Hematopoietic Cell Transplantation.
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New Approach Targets Gut Hormone To Lower Blood Sugar Levels
A research team led by Dr. Tony Lam at the Toronto General Research Institute and the University of Toronto discovered a novel function of a hormone found in the gut that might potentially lower glucose levels in diabetes.
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New Ovarian Transplant Technique Could Expand Use Of Procedure To Preserve Fertility
Two recent advancements in ovarian transplant techniques could potentially expand the availability of the procedure for women seeking to avoid fertility problems as they age, researchers reported Monday at a meeting of the European Society of Human Reproduction and Embryology, the AP/Yahoo! News reports. According to the AP/Yahoo! News, ovary transplants traditionally have been performed on women with cancer as a method of preserving fertility after chemotherapy or other treatments that can affect the reproductive system. The procedure involves removing the ovaries before treatment and re-implanting them after treatment is complete. Because only a handful of these procedures have been successful, ovarian transplants have been an option only for women with serious diseases. However, as more women delay having children until their 30s or 40s, researchers say the new techniques, in theory, could make it simpler for healthy younger women to have an ovary removed, frozen and then re-implanted later in life when they are ready to have children.The first study examined how many eggs were lost or preserved in fresh and frozen ovarian tissue of 15 young women prior to the start of cancer treatment. According to the study, there was no difference in the quantity of eggs in the fresh tissue and in the ovaries frozen using a new ultra-fast technique. The study found that about 50% of a woman"s eggs were lost using the traditional, slow-freezing methods of preserving the ovaries.The second study reported on a new surgical technique to restore an ovary"s function after transplantation. For the study, Pascal Piver of Limoges University Hospital and colleagues divided the transplant process into two separate procedures in an attempt to more quickly re-establish blood and hormone supplies to the ovary. In the first procedure, the researchers performed a graft of small pieces of ovarian tissue to prompt blood vessels to grow. They performed the ovary transplant three days later. The technique was successful in a woman who lost fertility because of treatment for sickle cell anemia.Sherman Silber, director of the St. Louis Infertility Center in Missouri and a researcher for the first study, said the new techniques "could dramatically expand our reproductive life span." He added, "This is not an experimental procedure for cancer patients anymore. The question is whether more women should be able to have this option" (Cheng, AP/Yahoo! News, 6/29).
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Frank, Dodd, Grassley Speak Their Minds

News outlets are searching out interesting quotes from players in the health reform debate. Sen. Charles Grassley, R-Iowa, remains on the fence about several provisions in a Democratic plan, The Washington Post reports: "Winning over the Senate Finance Committee"s ranking Republican would represent a major coup for Democrats and a rare defection from the GOP party line for Grassley, a populist at heart but a loyal Republican according to his voting record. ò€¦ Not even Grassley can tell where he eventually will end up, but he is making the most of the attention he is getting from the White House. Over lunch with Obama last month, the senator complained that certain Environmental Protection Agency pollution policies were harming Iowa farmers. He has since met with several senior White House officials and is negotiating a visit to his state by EPA Administrator Lisa P. Jackson" (Murray, 6/19). CongressDaily focused on Sen. Chris Dodd, D-Conn: "As the Senate Health, Education, Labor and Pensions Committee wrapped up a second day of public wrangling over a 600-page health overhaul, the panel"s Democratic leader said bipartisanship isn"t his top priority. "My goal here is to write a good bill. My goal is not bipartisanship," said Sen. Christopher Dodd, D-Conn., who is chairing the markup proceedings while HELP Chairman Edward Kennedy undergoes treatment for brain cancer. "That can help you write a good bill, but it is not an end in itself"" (Hunt, 6/19). ""Certainly, stalling it is not helping it at this point," Dodd said. "My job is to be fair and to keep the process moving forward,"" Dodd told Dow Jones Newswires (Yoest, 6/18). On the House side, Rep. Barney Frank, D-Mass., said he agrees with Obama that there are some places in Europe where single-payer systems work, CNSNews.com reports: "As prime minister of Britain, "Margaret Thatcher considered it a great attack on her when people said she was trying to pick apart health care," said Frank. "Britain goes way beyond a single-payer. That"s socialized medicine. Scandinavia, much of Western Europe," have a single-payer system that works" (Lucas, 6/19). Even as the interim communications director for the White House, Anita Dunn is focused on health care, The Washington Post reports in a separate story. ""As we like to say, if it was easy, somebody else would have done it," Dunn says. Dunn started out in Democratic politics in the late "70s, and she is well liked by the media and politicians for her no-nonsense, self-effacing style" (Romano, 6/19). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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