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Head-to-head Trial Demonstrates Viramune®`s Similar Efficacy And Superior Effect On Lipid Profile Compared To Atazanavir/ritonavir
Results from the ARTEN trial presented at the 5th International AIDS Society (IAS) conference in Cape Town, South Africa demonstrated non-inferiority regarding efficacy between Viramune® (nevirapine) and ritonavir boosted atazanavir (atazanavir/r) both combined with tenofovir and emtricitabine (Truvada ®). This head-to-head study also showed Viramune®Â´s more favourable effect on the lipid profile and now clearly confirms the combination"s place as an important first line therapy for patients with HIV.
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Diagnostic Evaluation Of PSA Recurrence And Review Of Hormonal Management After Radical Prostatectomy
UroToday.com - At present, no consensus exists on how patients with PSA recurrence after radical prostatectomy (RP) should be treated. Although patients with postoperative PSA recurrence frequently undergo androgen deprivation therapy (ADT) before evidence of metastatic disease, the benefit of this approach is uncertain. As no randomized studies are performed in this clinical setting there is no conclusive evidence that hormone therapy (HT) after RP will prolong survival or reduce morbidity.
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Scientists Discover A Fundamental Mechanism For Cell Organization
Scientists have discovered that cells use a very simple phase transition -- similar to water vapor condensing into dew -- to assemble and localize subcellular structures that are involved in formation of the embryo.
Medical Devices

Data Shows Incisionless Procedure Reverses Weight Gain

Patients who have regained weight after gastric bypass surgery now have access to an incisionless procedure that appears highly effective at reversing weight gain, according to data presented at the annual meeting of the American Society of Metabolic and Bariatric Surgeons. Santiago Horgan, MD, professor of surgery and director of the Center for the Treatment of Obesity at UC San Diego, presented six-month outcomes from a national registry of 116 patients who underwent the procedure, known as ROSE (Restorative Obesity Surgery, Endolumenal). "We believe this registry represents the largest collection of data showing the effectiveness, safety and durability of the ROSE procedure," said Horgan. "There are not many options to repair a failing gastric bypass. Invasive procedures to restore the anatomy are complicated and risky for most patients. In comparison, there were no significant complications associated with ROSE and most of the patients lost clinically relevant amounts of weight." To perform ROSE, a small, flexible endoscope and tools are inserted through the mouth, down the esophagus, and into the stomach pouch during an outpatient procedure. The tools, developed by USGI Medical Inc., are used to grasp, fold and stitch tissue to reduce both the diameter of the stomach opening and the volume of the stomach pouch. No cuts are made into the patient"s skin. The registry data showed that 88 percent of the patients stopped regaining weight after ROSE. Overall, these 96 patients lost an average 18 percent of their excess weight six months after the procedure. For the purposes of the registry, excess body weight is defined as anything over a body mass index rating of 55. One patient in the study lost 66 pounds or 84 percent of her excess weight during that six-month time period. Patients who were most successful losing weight after their original gastric bypass had the best results following the ROSE procedure. This subset of patients dropped 29 percent of their excess weight during the six months after ROSE. Up to 50 percent of patients who undergo gastric bypass surgery begin to regain weight after two years. This often occurs because the stomach pouch and stoma, the opening to the small intestine, slowly stretch out, allowing the patient to eat more without feeling full. University of California, San Diego


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